儿童人类免疫缺陷病毒相关性血小板减少性紫癜—附2例报告  

The human immunodeficiency virus-related thrombocytopenic purpura in children with 2 cases report

作　　者：张永红[1] 张莉[1] 杨箐[1] 段渊[1] 

机构地区：[1]首都医科大学附属北京儿童医院,100045

出　　处：《中国小儿血液》2005年第5期209-212,共4页China Child Blood

摘　　要：目的通过两例人类免疫缺陷病毒相关免疫性血小板减少性紫癜(HIV-ITP)特点的临床总结及相关文献复习,提高对本病的认识。方法临床病历分析及文献复习。结果2例儿童分别经输血感染HIV后5年和7年后出现血小板减少性紫癜(ITP)的症状,经相关检测确诊为HIV-ITP,经丙球冲击及激素治疗好转,但很快复发。结论ITP是HIV病人常见的血液系统表现,也常是HIV的首发症状之一,抗ITP治疗短期有效,长期疗效不佳,彻底治愈困难。Objective To report two cases with the human immunodeficiency virus -related thrombocytopenic purpura（ HIV - ITP） in children. A review of the literature and possible mechanism and treatment were presented. Methods 2 Cases reported and literature review. Results Two children patients developmented the manifestation of immune thrombocytopenic purpura（ ITP）after 5 and 7 years infecting HIV through blood transfusion. The transitory effect was good after intravenous immunoglobulin and steroid. But all of them recurrent soon. Conclusion ITP is a common hematologic disorder in patients infected with HIV and is also one of the first manifestation of HIV patients. The transitory effect was good after routine anti -ITP treatment but it is difficulty to cure.

关 键 词：人类免疫缺陷病毒免 疫性血小板减少性紫癜 儿童 

分 类 号：R725.5[医药卫生—儿科]