间硝基苯甲醛合成新工艺的研究  

Study on new synthesis of m-Nitrobenzaldehyde

作　　者：丁成荣[1] 吴德强[1] 来虎钦[1] 林环[1] 李万梅[1] 周瑛[1] 

机构地区：[1]浙江工业大学化学工程与材料学院,浙江杭州310032

出　　处：《浙江工业大学学报》2005年第6期605-607,共3页Journal of Zhejiang University of Technology

摘　　要：以苯甲醛为原料,与异丙基胺反应生成中间体苯甲醛缩亚胺,再用混酸硝化,然后水解,得到目标产物间硝基苯甲醛.重点对硝化反应的原料配比、反应温度、反应时间及水解时间进行了考察,得到硝化反应的原料配比为苯甲醛缩亚胺:硫酸(摩尔比)=1:7,苯甲醛缩亚胺:硝酸(摩尔比)=1:1.2,反应温度为10～15℃,反应时间为2 h,水解时间为2.5 h的较优工艺条件.收率88.4%,质量分数为99.1%.该法与直接硝化法比具有分离简单、收率高、产品纯度好的优点.The process of synthesizing rn-Nitrobenzaldehyde by nitration and hydrolysis of benzaldehyde was developed and investigated. The influences of the nitration of proportion substrate, reaction temperature, reaction time and of the hydrolysis of temperature were investigated. The yield was 88.4% with proportion substrate of alkylamine ＇ sulfuric acid= 1 ： 7, alkylamine ： nitric acid=1 -1.2, in the course of 10-15 ℃ and 2 h in nitration, and 2.5 h in hydrolysis. This method had the following advantages, simpler separation, better yield, higher purity.

关 键 词：间硝基苯甲醛 苯甲醛 缩亚胺 硝化 

分 类 号：TQ207[化学工程—有机化工]