CAl25、CAl53、CAl99、β-HCG联合检测在乳腺癌病情监测中的意义  

Significance on evaluation of extent of measuring CA125,CA153,CA199,β-HCG for patients with breast cancer

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作  者:胡春梅[1] 李亚荣[1] 夏大文[1] 朱睿[2] 

机构地区:[1]吉林大学第二医院肿瘤内科,长春130021 [2]吉林省医疗器械检验所,长春130021

出  处:《激光杂志》2005年第6期100-100,共1页Laser Journal

摘  要:目的:探讨CA系列及β-HCG联合检测在乳腺癌病情监测中的意义。方法;利用双抗体夹心法对84例乳腺癌患者进行CAl25、CAl53、CAl99、β-HCG的检测,并观察其在不同TNM分期及其不同病理水平的变化。结果:TNM临床分期越晚,4种肿瘤标志物水平越高;不同病理类型的患者之间4种肿瘤标志物水平无显著性差异:联合检测可提高病情评估的灵敏度。结论;该4种肿瘤标志物在乳腺癌病情监测方面可为临床提供有价值的资料。Objective: To study'the clinical significance of carcinoma associated antigen ( CA125, CA153, CA199 )and human chorionic gonadotropin(β - HCG)in evaluation of disease extent and nronitofing metastasis and recun^nce of breast cancer. Methods: These tumor markers in serum were measured in 84 patients with breast cancers, and change of the markers were observed in these patiynts with different stage and pathohistological evidence. Results:The later the stage of TNM of breast cancer, the higher levels of 4 tumor markers would be revealed. There was no significant difference in the levels of 4 tumor markers for patients with different pathohistological evidence. Combination of these tumor markers increased sensitivity of measurement. Conclusions : Measurement of CA125, CA153, CA199 and β-HCG in serum provided useful iinformation for evaluation of disease extent in patients with breast cancer.

关 键 词:乳腺癌 CA125 CA153 CA199 Β-HCG 

分 类 号:TN248.1[电子电信—物理电子学]

 

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