形态正常精子百分率与顶体酶活性的关系  

To explore the relationship between sperm morphology and sperm acrosin activity

作　　者：侯毅[1] 刘媛[2] 刘睿智[2] 薛百功[2] 马玉涵[2] 江露[2] 

机构地区：[1]吉林大学中日联谊医院泌尿外科,130021 [2]吉林大学基础医学院细胞生物学教研室

出　　处：《中国妇幼保健》2005年第23期3153-3154,共2页Maternal and Child Health Care of China

基　　金：吉林省科技厅资助项目(20030433)

摘　　要：目的:探讨精子形态与精子顶体酶活性的关系。方法:对737例男性不育患者采用分光光度比色法测定顶体酶活性,采用精子形态检测系统下人工修正方法分析精子形态。结果:精子形态正常组的顶体酶活性明显高于精子形态异常组,两组间比较差异显著(P<0.05);顶体酶活性正常组形态正常精子百分率明显高于顶体酶活性异常组形态正常精子百分率,两组间比较差异亦具有显著性(P<0.001);顶体酶活性与形态正常精子百分率间呈显著正相关关系(r=0.172,P<0.001)。结论:精子形态可影响精子顶体酶活性。Objective： To study the relationship between sperm morphology and acrosin activities. Methods： The sperm morphology were analyzed by automated sperm morphology analyzer （ASMA） and the sperm acrosin activities were determined by spectrophotometer. Results： The acrosin activities of abnormal sperm morphology group are lower than that of normal sperm morphology group （P 〈 0. 05） , The normal morphology sperm rate of abnormal acrosin group is lower than that of normal acrosin group （P 〈 0. 001 ） . There were significantly positive correlation relationship between the acrosin activities and the rate of normal sperm morphology （ r = 0. 172, P 〈 0. 001） . Conclusion： The sperm morphology could affect sperm acrosin activities.

关 键 词：男性不育 精子形态 精子顶体酶 

分 类 号：R711.6[医药卫生—妇产科学]