大鼠直肠壁内淋巴管的微细分布及超微结构  

The fine distribution and ultrastructure of intramural lymphatics in rats' rectum

作　　者：董国刚 吕岩红[2] 李玉兰[2] 施一敏 赵玲辉[2] 肖建兵[2] 

机构地区：[1]南京军区空军司令部机关医院放射科,南京210018 [2]哈尔滨医科大学解剖教研室

出　　处：《解放军医学杂志》2005年第11期1000-1002,共3页Medical Journal of Chinese People's Liberation Army

基　　金：黑龙江省教育厅基金资助课题(编号10553050)

摘　　要：目的观察大鼠直肠壁内淋巴管的分布和形态、结构特点,为探讨直肠癌淋巴道转移的机制提供形态学依据。方法用半薄、超薄切片、光镜和电镜下观察大鼠直肠淋巴管的微细分布和超微结构。结果直肠壁内的毛细淋巴管见于黏膜固有层深部和肛梳区真皮乳头层;在黏膜下层和肛梳区的网状层、皮下组织以及肌层和浆膜层内均有毛细淋巴管和淋巴管,直肠壁内毛细淋巴管的超微结构具有一般毛细淋巴管超微结构的特点,内皮细胞连接有重叠、嵌插和端端连接3种类型,处于开放状态约占21%;胞质内含有一般的细胞器,并含有大量的囊泡。结论齿状线以上直肠壁各层淋巴管的分布与其他部位消化管壁的相似;齿状线以下的淋巴管分布与皮肤的相似,提示在直肠内组织液和大分子物质的转运主要通过内皮细胞的连接开放和囊泡系统。Objective Observe the fine distribution and morphologic feature of the intramural lymphatics in rats＇ rectum and to provide the morphological evidence for studying the mechanism of lymphous metastasis of rectum carcinoma. Methods The intramural lymphatics of rectum in rats were studied by light and electron microscopy to obtain some data regarding their fine distribution. Results The intramural capillary lymphatics of rats＇ rectum were observed in deep lamina propria of tunica membrane and the dermal papilla layer of anal pectin. The intramural capillary lymphatics and lymphatics were both ohserved in tela suhmucosa, reticular layer, hypodermis and intermuscular and serosa. The capillary lymphatics in rectums＇ wall have the similar ultrastructure feature to normal ones. Three kinds of endothelial cells junctions are overlapping-junctions, embedding-junctions and end to-end-type junctions. About 21% of cell-junctions are opening types. There are normal organelles and many vesicals in the endothelial of capillary lymphatics. Conclusion The distribution of lymphatics in every layer of dentate line upwards are similar to other digestive tubes＇. The distribution of lymphatics in anal pecten of rats rectum are similar to cutis. The results show that big molecule substance and tissue hydrolysate are transporting mainly by openingjunction of endothelial cells and the vesicle system.

关 键 词：直肠淋巴管 微细分布 超微结构 大鼠 

分 类 号：R322.27[医药卫生—人体解剖和组织胚胎学]