N-(4-安替比林基)-N′-芳氧乙酰基硫脲的合成及其生物活性  

Synthesis and Biological Activity of N-(4aminoantipyrine)-N′-Aryloxyacetyl Thiourea

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作  者:吴玮琳[1] 叶文法[1] 杨曼丽[1] 汪焱钢[1] 

机构地区:[1]华中师范大学化学学院

出  处:《应用化学》2005年第12期1351-1353,共3页Chinese Journal of Applied Chemistry

基  金:国家自然科学基金资助项目(20072009);湖南教育厅科学研究资助项目(03C042)

摘  要:Seven new N-(4-aminoantipyrine)-N′-aryloxyaceyl thioureas were synthesized.Their structures were confirmed by 1H NMR,IR and elemental analysis.The biological activity tests show that some target compounds have good activity as plant growth regulators,in particular N-(4-aminoantipyrine)-N′-o-(nitroaryloxyacetylthiourea) has an excellent cytokinin activity of 44.1%,which approaches the cytokinin activity of 6-furylmethylamino purine,which is 45.4%.Seven new N-(4-aminoantipyrine)-N'-aryloxyaceyl thioureas were synthesized. Their structures were confirmed by ^1H NMR, IR and elemental analysis. The biological activity tests show that some target compounds have good activity as plant growth regulators, in particular N-( 4-aminoantipyrine )-N'-o- nitroaryloxyacetylthiourea has an excellent cytokinin activity of 44. 1%, which approaches the cytokinin activity of 6-furylmethylamino purine,which is 45.4%.

关 键 词:氨基安替比林 酰基硫脲 合成 生物活性 细胞分裂素 

分 类 号:O623.7[理学—有机化学]

 

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