广州地区女性下生殖道感染致病微生物分析  

To study the microorganism of low genitalia infection among Guangzhou female

作　　者：张帝开[1] 覃春容[1] 李秀云[1] 史成军[2] 胡斌[2] 程钢[2] 杨冬梓[1] 

机构地区：[1]中山大学附属第二医院妇产科,广东广州510120 [2]中山大学达安基因股份有限公司,510070

出　　处：《中国微生态学杂志》2005年第6期417-418,共2页Chinese Journal of Microecology

基　　金：广东省卫生厅基金(A2003215);广州市科技局基金(2004Z3-E0131)

摘　　要：目的对广州地区女性下生殖道感染致病微生物状况进行调查,用以指导临床正确诊断治疗。方法对以外阴瘙痒及白带增多为主诉的妇女患者进行临床检查,先取阴道分泌物进行pH、胺试验及假丝酵母菌、滴虫和线索细胞检查,同时采用特制密封棉拭子宫颈管内取样,然后采用重量差减法,求出分泌物的重量,采用荧光定量PCR测定解脲脲原体、淋球菌、沙眼衣原体,可疑部位取材作HSV和HPV检测及梅毒血清学检查。结果在533例入选患者中,解脲脲原体感染345例占64.7%,沙眼衣原体感染142例占26.6%,阴道假丝酵母菌病117例占22%,非特异性阴道炎81例占15%,细菌性阴道病17例占0.03%。尖锐湿疣12例占0.02%。淋病5例,梅毒4例,生殖器疱疹2例,滴虫阴道炎2例。结论解脲脲原体、沙眼衣原体、阴道假丝酵母菌病是当前广州地区女性下生殖道感染的主要致病微生物,在选用抗生素时要兼顾解脲脲原体、沙眼衣原体。Objective To determine the microorganism of low genitalia infection among Guangzhou female who attended to department of obstetrics and gynecology clinic. In order to guide the correct clinical diagnosis and treatment. Methods Physical examination was undertaken for all patients with vulvae itching and vaginal discharge manifold. Swabs of vaginal discharge were tested for pH, aminet test, candida,trichomonas and clue cells. We use sealed cotton swab to sample in cervix. We get the weight of secretion by differential subtract method then to detect for N. gonorrhoea,U, ureaplasma and Chlamydia by fluorescent quantitative PCR（FQ-PCR）. The specimen from suspected lesions were tested for HSV and HPV and the serological tests were carried out for syphilis. Result The detected rate of U. urealyticum,Chlamydia,Candida and non-specific vaginitis was 64. 5%,26. 6%, 22% and 15% respectively. Conclusion The main of the microorganism in this group were U. urealvticum, Chlamydia ,and Candida.

关 键 词：阴道炎 解脲脲原体 沙眼衣原体 

分 类 号：R378[医药卫生—病原生物学]