糖尿病对冠状动脉狭窄左室舒张末压的影响  

Impact of diabetes mellitus on left ventricular end-diastolic pressure of patients with coronary artery stenosis

作　　者：汤沂[1] 江时森[1] 黄浙勇[1] 

机构地区：[1]南京军区南京总医院/南京大学医学院临床学院心血管内科,江苏南京210002

出　　处：《心脏杂志》2005年第6期570-572,共3页Chinese Heart Journal

摘　　要：目的:探讨糖尿病对冠状动脉狭窄患者左室舒张末压的影响。方法:选择行冠状动脉造影及左室造影的冠脉狭窄的患者662例,将之分为冠状动脉狭窄并发糖尿病组(CHD+DM组)110例,及单纯冠状动脉狭窄组(CHD组)552例,所有患者都进行左室造影,测定左室射血分数(LVEF)及左室舒张末压(LVEDP)。结果:两组患者LVEF间无明显差异,但CHD+DM组患者的LVEDP显著高于CHD组。结论:糖尿病可以加重冠状动脉狭窄对左室舒张功能的损害,引起LVEDP增高。AIM： To study the impact of diabetes mellitus on left ventricular end-diastolic pressure of patients with coronary artery stenosis. METHODS： Among the recruited 662 patients with significant coronary artery stenosis, 110 patients were complicated with diabetes mellitus （CHD ＋ DM group） and 552 patients without diabetes （CHD group）. All patients were examined using left ventricular angiogra- phy. Ejection fraction （LVEF） and enddiastolic pressure of left ventricular （LVEDP） were measured. RESULTS： LVEDP in patients of CHD ＋ DM group was significantly higher than that in CHD group, while there was no significant difference in LVEF between two groups. CONCLUSION： Diabetes mellitus aggravates the ventricular function of patients with coronary artery stenosis, especially the diastolic function, which can result in the increasing of LVEDP.

关 键 词：左室射血分数 左室舒张末压 左室造影 糖尿病 

分 类 号：R543.3[医药卫生—心血管疾病]