血压偏高儿童糖耐量试验胰岛素测定  

Insulin Levels of Glucose Tolerance Test in Borderline Hypertensive Children

作　　者：郭行平[1] 彭建风 李家宜[1] 李竞[1] 刘敏[1] 

机构地区：[1]首都儿科研究所,北京100020

出　　处：《高血压杂志》1996年第2期92-94,共3页Chinese Journal of Hypertension

基　　金："八.五"国家科技攻关项目(85-915-01-04)

摘　　要：目的研究血压偏高儿童的血糖(SG)及胰岛素(IS)改变情况。方法对血压偏高儿童和对照者各50例进行葡萄糖耐量试验(OGTT),测定 SG、IS 浓度。结果血压偏高组空腹SG、IS 和 OGTT(IS)(GS)反应曲线下面积(AUC)及反应曲线下面积 IS 与 GS 比值(AUC IS/SG)显著增高(P<0.05～0.01);血压偏高组肥胖儿 OGTT(SG)及 SG AUC,空腹 IS 及OGTT(IS)、IS AUC 及 AUC IS/SG显著高于高血压非肥胖者;血压偏高组非肥胖者空腹 SG、IS 及 OGTT(IS)及 AUC IS/SG 高于对照组非肥胖者。结论高血压、肥胖均存在胰岛素抵抗。Aim Investigate the serum glucose (SG)and insulin(IS)levels in borderline hyperten- sive children.Methods The SG and IS of 50 bor- derline hypertensive children and 50 normal controls were determined in oral glucose tolerance test (OGTT).Results The fasting SG and IS was in- creased,OGTT(IS)area under curve(AUC)and AUC IS/SG were significantly increased both before and after OGTT in borderline hypertensive children (P<0.05～0.01).OGTT(GS),AUC and fasting IS,OGTT(IS)AUC and AUC IS/SG were markedly increased in borderline hypertensive children with obesity than those with non-obesity.Conclusion The insulin resistance is closely related to hyperten- sion and obesity.

关 键 词：血压偏高儿童 糖耐量试验 胰岛素抵抗 高血压 

分 类 号：R725.441[医药卫生—儿科]