新型苯并噁唑(噻唑)衍生物的合成与表征  

Synthesis of Novel Benzoxazole and Benzothiazole Derivatives

作　　者：张英俊[1] 谭小华[1] 邵光[1] 彭志鸿[1] 安德烈[1] 

机构地区：[1]湖南大学化学化工学院,湖南长沙410082

出　　处：《合成化学》2005年第6期555-559,共5页Chinese Journal of Synthetic Chemistry

基　　金：国家教育部留学人员科研启动基金资助项目[(1998)679]

摘　　要：通过N-氯乙酰或N,N′-二氯乙酰取代的含氮杂环中间体,4,5-二氯-2-苯基-3-哒嗪酮分别与2-巯基苯并噁唑和2-巯基苯并噻唑反应,合成了8个未见文献报道的苯并噁唑和苯并噻唑衍生物,其结构经1H NMR,IR,MS及元素分析确认。Eight novel benzoxazoles and benzothiazoles were synthesized by the reaction of N-chloroacetyl or N,N＇-dichloroacetyl substituted nitrogen-containing heterocycles, and 4,5-dichloro-2-phenyl-3-pyridazinone with 2-mercaptobenzoxazole and 2-mercaptobenzothiazole, respectively. Their structures were characterized by ^1H NMR, IR, MS and elemental analysis.

关 键 词：含氮杂环 苯并噁唑 苯并噻唑 合成 

分 类 号：O626.4[理学—有机化学]