Characteristics of hyperpolarization-activated inward current in rabbit pulmonary vein muscle sleeve cells  

作　　者：LIU Jie HUANG Cong-xin JIANG Hong BAO Ming-wei CAO Feng WANG Teng 

机构地区：[1]Department of Cardiology, Renmin Hospitoal of Wuhan University,Wuhan 430060, China

出　　处：《Chinese Medical Journal》2005年第23期2014-2019,共6页中华医学杂志（英文版）

摘　　要：Atrial fibrillation （AF） is one of common ,sustained tachyarrhythmias and is one of the major causes of stroke. Recent clinical studies have shown that ectopic activities in pulmonary vein muscle sleeves （PVMSs） are important not only for the initiation of AF but also for its maintenance. Four-phase spontaneous depolarization could be observed in PVMS after the tissue was pre-treated with ryanodine or when atrial pressure was elevated. These data showed the distinct electrophysiology characteristics of PVMS.Atrial fibrillation （AF） is one of common ,sustained tachyarrhythmias and is one of the major causes of stroke. Recent clinical studies have shown that ectopic activities in pulmonary vein muscle sleeves （PVMSs） are important not only for the initiation of AF but also for its maintenance. Four-phase spontaneous depolarization could be observed in PVMS after the tissue was pre-treated with ryanodine or when atrial pressure was elevated. These data showed the distinct electrophysiology characteristics of PVMS.

关 键 词：electrophysiology· atrial fibrillation ·veins 

分 类 号：R543.2[医药卫生—心血管疾病]