Synthesis and Crystal Structure of 8-methyl-5-phenyl-4-thia-6-aza-spiro [2.5] oct-5-en-7-ol  

作　　者：YU Lei WU Lu-Ling XIE Ming-Hua SHI Lei HUANG Xian 

机构地区：[1]Department of Chemistry, Zhejiang University, Xixi Campus, Hangzhou 310028, China

出　　处：《Chinese Journal of Structural Chemistry》2005年第12期1408-1410,共3页结构化学（英文）

摘　　要：The crystal structure of 8-methyl-5-phenyl-4-thia-6-aza-spiro [2.5] oct-5-en-7-ol （C13H15NOS, Mr=233.32） has been determined by single-crystal X-ray diffraction analysis. The crystal belongs to orthorhombic, space group Pbca with a = 8.0929（8）, b = 12.9749（13）, c = 23.841（2）A, V = 2503.4（4）A^3, Z = 8, Dc = 1.238 g/cm^3, μ=0.237mm^-1, F（000） = 992, R = 0.0559 and wR = 0.1469. The X-ray diffraction analysis shows that two molecules of the title compound are connected with each other by O-H-N hydrogen bonds.The crystal structure of 8-methyl-5-phenyl-4-thia-6-aza-spiro [2.5] oct-5-en-7-ol （C13H15NOS, Mr=233.32） has been determined by single-crystal X-ray diffraction analysis. The crystal belongs to orthorhombic, space group Pbca with a = 8.0929（8）, b = 12.9749（13）, c = 23.841（2）A, V = 2503.4（4）A^3, Z = 8, Dc = 1.238 g/cm^3, μ=0.237mm^-1, F（000） = 992, R = 0.0559 and wR = 0.1469. The X-ray diffraction analysis shows that two molecules of the title compound are connected with each other by O-H-N hydrogen bonds.

关 键 词：synthesis crystal structure cyclopropane-derived 

分 类 号：O624.2[理学—有机化学]