Synthesis and Crystal Structure of N-cyclopropyl-9 -(3,4-dicholophenyl)-1,2,3,4,5,6,7,8,9,10-decahydroacridine -1,8-dione under Microwave Irradiation  

作　　者：FENG You-Jian JIA Run-Hong TU Shu-Jiang ZHANG Xiao-Jin JIANG Bo ZHANG Yan ZHANG Jun-Yong 

机构地区：[1]Department of Chemistry, Xuzhou Normal University, Key Laboratory of Biotechnology on Medical Plant, Xuzhou, Jiangsu 221116, China

出　　处：《Chinese Journal of Structural Chemistry》2005年第12期1457-1461,共5页结构化学（英文）

基　　金：This work was supported by the National Natural Science Foundation of China (No. 20372057), the Natural Science Foundation of the Jiangsu Province (No. BK2001142), the Suzhou University Organic Syntheses Open Laboratory of Jiangsu Province (No. S8109111) and the Key Lab of Biotechnology for Medicinal Plants of Jiangsu Province (No. 01AXL 14)

摘　　要：The N-cyclopropyl-9-（3,4-dicholophenyl）- 1,2,3,4,5,6,7,8,9,10-decahydroacri- dine-1,8-dione was synthesized by the reaction of 1,3-cyclohexanedione, N-cyclopropylamine and 3,4-dicholoaldehyde in water and glycol under microwave irradiation. Its crystal structure was determined by single-crystal X-ray diffraction analysis. It possesses P212121 space group, with a = 9.9103（5）, b = 13.3597（8）, c = 14.5633（8）A, V= 1928.16（18）A3 ,Mr = 402.30, Z = 4, Dc= 1.386 g/cm^3, 2 = 0.7107A,μ（MoKα）=0.354mm^-1 and F （000） = 840. The structure was refined to R = 0.0280 and wR = 0.0757. In the structure, the pyridine ring adopts a boat conformation.

关 键 词：ACRIDINE SYNTHESIS microwave irradiation crystal structure 

分 类 号：O626.326[理学—有机化学]