冠状动脉钙化积分预测老年冠心病的相关研究  

Research on predicting coronary artery disease by coronary artery calcification score

作　　者：卢慧玲[1] 王汐[1] 刘白鹭[1] 刘明宇[1] 陈延军[1] 伴场信之 笠井贵久男 

机构地区：[1]哈尔滨医科大学附属二院老年病科,黑龙江省哈尔滨市150086 [2]独协医科大学内科

出　　处：《实用老年医学》2005年第6期293-294,297,共3页Practical Geriatrics

基　　金：黑龙江省科技攻关项目基金资助课题(GC04C30102)

摘　　要：目的进一步探讨预测老年冠心病的新指标,预防心血管事件的发生。方法对≥60岁老年人66例(冠心病48例,非冠心病18例)进行多层螺旋CT(MSCT)冠状动脉扫描和计算机自动测定冠状动脉钙化积分(CACS),对CACS结果进行分析。结果老年冠心病组的CACS明显高于非冠心病组(P<0·01)。3支血管钙化者CACS明显高于1支及2支血管钙化者,且钙化发生在任意血管段都有明确意义(P<0·01,P<0·05)。结论CACS优于传统危险因子,可作为预测冠心病的新指标之一。Objective To investigate the new indication of predicting coronary artery disease （CAD） in the elderly subjects in order to prevent the cardiovascular events. Methods Coronary artery calcification （CAC） was scanned and its score（CACS） were measured automatically by muhislice spiral computed tomography （MSCT） in 66 elderly patients （48 patients with CAD and 18 subjects without CAD）. The results of CACS were analyzed. Results The CACS of subjects with three-vessel calcification were significantly higher than those with single or two-vessel calcification. When every branch of coronary artery was observed, CACS had significant difference between CAD group and non-CAD group （ P 〈 0. 01, P 〈 0. 05 ）. Conclusions CACS is better than traditional cardiovascular risk factors and can be used as a new indication to predict CAD.

关 键 词：冠状动脉疾病 体层摄影术 X线计算机 老年人 

分 类 号：R542.2[医药卫生—心血管疾病]