氮杂冠醚取代非对称双Schiff碱配合物模拟水解酶催化PNPP水解研究  

Study on Aza Crown Ether Substituted Unsymmetry Bis-schiff base Complexes as Mimic Hydrolytic Enzyme Catalyze PNPP Hydrolysis

作　　者：冯发美[1] 王莹[1] 刘富安[1] 徐斌[1] 李建章[1] 

机构地区：[1]四川理工学院化学系绿色化学重点实验室,四川自贡643000

出　　处：《四川理工学院学报（自然科学版）》2005年第4期65-68,共4页Journal of Sichuan University of Science & Engineering(Natural Science Edition)

摘　　要：将4种非对称双Schiff过渡金属配合物作为仿水解酶模型催化羧酸酯(PNPP)水解。探讨了 Schiff过渡金属配合物催化PNPP水解的动力学;提出了配合物催化PNPP水解的动力学模型。结果表 明,在25℃条件下随着缓冲溶液pH值的增大,配合物催化PNPP水解速率提高,并表现出好的催化活 性。Two aza crown ether substituted unsymmetry bis-Schiff base transition-mental complexes have been used as mimic hydrolytic enzyme model catalyzing carboxylic acid esters （PNPP） hydrolysis. The kinetics on PNPP hydrolysis catalyzed by these complexes are investigated. The kinetic mathematical model of PNPP cleavage catalyzed by these complexes is proposed. The results show that the rate for the catalytic PNPP hydrolysis is increased following the increase of pH of the buffer solution; four complexes exhibite high activity, in the catalytic PNPP hydrolysis.

关 键 词：氮杂冠醚 非对称双Schiff碱 过渡金属配合物 PNPP水解 

分 类 号：O441.1[理学—电磁学]