酯交换法合成壳聚糖季铵盐的研究  

Synthesis and Characterization of the Quaternary Ammonium Salt of Chitosan

作　　者：易方平[1] 王源升[2] 孙宗林[1] 

机构地区：[1]海军工程大学理学院,湖北武汉430033 [2]海军工程大学训练部,湖北武汉430033

出　　处：《精细与专用化学品》2005年第24期19-21,24,共4页Fine and Specialty Chemicals

摘　　要：以三乙胺、氯乙酸乙酯和壳聚糖等为原料,采用酯交换法合成了壳聚糖季铵盐。用红外光谱分析确定了合成壳聚糖季铵盐的结构。并探讨了最佳合成条件:壳聚糖与季铵化的氯乙酸乙酯物质的量之比为1∶3,反应温度为90℃,反应时间5·0h,季铵化产率可达99%。Quaternary ammonium salt of chitosan was synthesized starting from chitosan, triethylamine and ethyl chloroacetate by ester exchange reaction, Molecular structure of the product was identified by IR, The effect of reaction conditions on product performances was studied. As a result, the optimum conditions were as follows：n（chitosan） ： n（ quaternary ammonium chloroacetate） = 1 ： 3, reaction temperature was 90℃ and reaction time was 5 hours, The product yield of 99% could be reached.

关 键 词：壳聚糖 季铵盐 酯交换法 三乙胺 氯乙酸乙酯 

分 类 号：O631[理学—高分子化学]