铜中毒对雏鸡血液生化指标影响的研究  

Effect of Copper Toxicity on Blood Biochemical Parameters in Broilers

作　　者：崔恒敏[1] 杨光[1] 彭西[1] 邓俊良[1] 黎得兵[1] 

机构地区：[1]四川农业大学动物科技学院

出　　处：《畜牧兽医学报》2005年第12期1329-1333,共5页ACTA VETERINARIA ET ZOOTECHNICA SINICA

基　　金：国家自然科学基金资助项目(30471304);四川省教育厅和科技厅重点资助项目

摘　　要：1日龄艾维茵肉鸡健雏180只,随机分为3组,分别喂以对照日粮(Cu 11.92 mg/kg)、铜中毒I日粮(Cu650 mg/kg)和铜中毒II日粮(Cu 850 mg/kg)6周,以血液病理学方法观察铜中毒对雏鸡血液生化指标的影响。铜中毒Ⅱ组、铜中毒I组雏鸡分别于2周龄和3周龄开始出现临床症状,分别死亡7只和3只。血液生化指标变化表现为红细胞胞体和胞核变形;红细胞数量和血红蛋白含量显著降低(P<0.05或P<0.01),血清谷草转氨酶、乳酸脱氢酶活性和血清铜含量显著升高(P<0.05或P<0.01),血清铜蓝蛋白活性显著下降(P<0.01)。结果表明,铜中毒对雏鸡的生长发育和上述血液生化指标影响明显。The experiment was conducted to study the effect of copper toxicity on blood findings in chickens, 180 one-day-old Avian broilers were divided into three groups, and fed on diets as follow. （1）control （Cu 11.92 mg/kg）, （2）copper toxic Ⅰ （Cu 650 mg/kg） and （3）copper toxic Ⅱ （ Cu 850 mg/kg） for six weeks. The signs began to appear at the 2nd week in copper toxic group Ⅱ and at the 3rd week in copper toxic group Ⅰ. Some of affected chickens died during the experiment. Hematopathologically, red cells in toxic groups Ⅰ and Ⅱ became deformed. The populations of red cells, hemoglobin contents and serum caeruloplasmin activity were much lower, and the serum copper concentrations, activities of lactate dehydrogenase and glutamic-oxaloacetic transaminase were much higher in copper toxic groups than in control group. Mechanism of copper toxicity on blood findings is also discussed.

关 键 词：铜中毒 血液生化指标 雏鸡 

分 类 号：S856.9[农业科学—临床兽医学]