青春前期女童钙代谢实验研究  

STUDY OF CALCIUM METABOLISM IN PREMENARCHE CHINESE GIRLS

作　　者：肖新才[1] 苏宜香[1] 罗晓林[1] 

机构地区：[1]中山大学公共卫生学院营养系,广州510080

出　　处：《营养学报》2005年第6期517-520,共4页Acta Nutrimenta Sinica

基　　金：国家自然科学基金(No.30271120)

摘　　要：目的:研究我国青春前期女童钙代谢状况,初步探讨该时期女童钙需要量。方法:选择49名处于生长突增期、未月经初潮的青春前期女童,采用经典钙代谢实验方法,在600～1500mg/d范围内设计4个不同的钙摄入剂量组,观察研究对象的钙代谢状况。结果:在600～1500mg/d钙摄入量范围内,各组对象钙表观钙吸收率未发现差别,平均吸收率为(53±0.12)%(范围52%～55%)。采用非线性回归模型对钙摄入量和钙储留量的关系进行拟合,钙摄入量在500mg/d时,钙储留量处于较低水平,钙摄入量在500～1000mg/d时,储留量快速增加,当钙摄入量达到1100mg/d时,钙储留量稳定在500mg/d左右的平台水平。结论:我国青春前期女童钙的表观吸收率为(53±0.12)%;青春前期女童达到最大钙储留量的最低钙摄入量是1100mg/d。Objective： To investigate the characteristics of calcium metabolism and identify the calcium intake that produces plateau retention in premenarche Chinese girls. Method： Forty-nine healthy premenarche Chinese girls （9-11.5 y） were recruited, and divided into four groups respectively receiving one of four different doses of calcium intakes for 6 d, 600 mg （usual diet）, 900 mg （containing 250 ml milk）, 1200 mg （containing 250 rnl milk and 750 mg CaCO3） and 1500 mg calcium （250 rnl milk and 1500 mg CaCO3） per day. Calium in 3-day urine and stool, and 3-d duplicated food samples were collected to assess the calcium equilibrium during the treatment period. Results： There were no significant differences in apparent calcium absorption among the four groups （55%, 53%, 52% and 52%）. The relationship between calcium intake and calcium retention was fitted into a non-liner regression model which showed that the calcium retention was approaching the plateau when calcium intake reached 1100mg/d. Conclusion： The apparent calcium absorption was 53%±0.12% in Chinese premenarche girls with dietary calcium intakes ranged between 600 to 1500 mg/d. Calcium retention approached its plateau when calcium intake reached 1 100 mg/d in Chinese premenarche girls.

关 键 词：钙代谢 钙吸收率 青春前期 女童 

分 类 号：R179[医药卫生—妇幼卫生保健]