103例肝移植术后细菌感染危险因素分析  

Risk factors of bacterial infection after orthotopic liver transplantation:an analysis of 103 cases

作　　者：林浩铭[1] 李波[2] 霍永忠[3] 魏永刚[2] 严律南[2] 黄韬[2] 雷黎明[4] 

机构地区：[1]中山大学附属第二医院肝移植中心,广州510120 [2]四川大学华西医院肝移植中心,成都610041 [3]广东省中医院,广州510120 [4]四川大学华西医院麻醉科,成都610041

出　　处：《中国实用外科杂志》2005年第12期734-736,共3页Chinese Journal of Practical Surgery

摘　　要：目的分析肝移植病人术后各类细菌感染的发生率及其危险因素.方法回顾性分析四川大学华西医院2000～2003年施行的103例肝脏移植病人的临床资料.选取围手术期45个独立变量,经单变量分析及logistic回归分析,筛选与术后感染相关的危险因素.结果 52例病人术后发生77次细菌感染,感染率为50.49%(52/103);G-需氧菌占67.8%(103/152),G+需氧菌占32.2%(49/152).手术时间、呼吸机带机时间、 TPN支持时间与术后早期细菌感染有关.结论肝移植术后易发生细菌感染,针对其危险因素积极采取预防措施是降低术后感染率的主要措施.Objective To investigate the incidence and risk factors of bacterial infection after liver transplantation. Methods The clinical data of 103 case of liver transplantation admitted between 2000 and 2003 in West China Hospital of Sichuan University were analyzed retrospectively. Forty-five independent variables related to perioperative conditions were analyzed. Univariate analysis and logistic regression analysis were performed to screening the factors correlating to infective complication. Results Fifty-two cases developed 77 infection episodes. The infection rate was 50.49% （52/103）. Post-operative infection of G^- and G^＋ bacteria accounted for 67.8% （103/152）and 32.2% （49/152）respectively. It was identified that duration of operation, mechanical ventilation and TPN support were related to postoperative infection, Conelusions The liver transplantation recipients are susceptible to bacterial infections. Preventive measures aimed at risk factors are the main measures for reducing the incidence of postoperative bacterial infection.

关 键 词：肝移植 细菌感染 

分 类 号：R6[医药卫生—外科学]