马蔺地下部分的化学成分  

Chemical Constituents of Underground Parts of Iris lactea

作　　者：王昕[1] 秦民坚[1] 黎路[1] 叶文才[1] 

机构地区：[1]中国药科大学中药学院,南京210038

出　　处：《中国药科大学学报》2005年第6期517-519,共3页Journal of China Pharmaceutical University

基　　金：国家自然科学基金资助项目(No.30170103)~~

摘　　要：目的:研究鸢尾科鸢尾属植物马蔺(Iris lacteaPall.var.chinensis(Fisch.)koidz.)地下部分的化学成分。方法:采用70%乙醇提取,硅胶柱层析分离及重结晶等方法分离其化学成分,通过波谱及化学方法进行结构鉴定。结果:分离并鉴定了10个化合物,分别为:5-羟基-7-甲氧基黄酮(tectochrysin,Ⅰ)、5,2′-二羟基-6,7-亚甲二氧基二氢黄酮(5,2-′dihydroxy-6,7-methylenedioxyflavanone,Ⅱ)、5,7-二羟基-6,2′-二甲氧基异黄酮(5,7-dihydroxy-6,2-′dimethoxyisoflavone,Ⅲ)、4′,5-二羟基-6,7-二甲氧基异黄酮(4′,5-dihydroxy-6,7-dimethoxyisoflavone,Ⅳ)、4′,5,7-三羟基-6-甲氧基异黄酮(tectorigenin)(4′,5,7-trihydroxy-6-methoxyisoflavone,Ⅴ)、5,3′-二羟基2′-甲氧基-6,7-亚甲二氧基异黄酮(5,3-′dihydroxy-2-′methoxy-6,7-methylenedioxyisoflavone,Ⅵ)、5,2′-二羟基-6,7-亚甲二氧基异黄酮(5,2′-dihydroxy-6,7-methylenedioxyisoflavone,Ⅶ)i、risoid D(Ⅷ)i、risoid A(Ⅸ)和十七烷酸(heptadecanoic acid,Ⅹ)。结论:这些化合物均为在该植物中首次分得,其中化合物Ⅵ为本属植物中首次发现。AIM： To study the chemical constituents of the underground parts of Iris lactea Pall. var. chinensis （Fisch.） koidz.. METHODS： Extracted with 70% alcohol, isolated by column chromatography on silica gel, and purified by recrystallization. RESULTS： Ten compounds were isolated from Iris lactea. On the basis of the physical properties and spectral data, the structures were identified as tectochrysin （Ⅰ）; 5, 2＇-dihydroxy-6, 7- methylenedioxyflavanone （Ⅱ）; 5, 7-dihydroxy-6, 2＇-dimethoxyisoflavone （Ⅲ）; 4＇, 5-dihydroxy-6, 7- dimethoxyisoflavone （Ⅳ）; 4＇, 5, 7- trihydroxy -6-methoxyisoflavone （Ⅴ）; 5, 3＇-dihydroxy-2＇-methoxy-6, 7- methylenedioxyisoflavone （Ⅵ）; 5, 2＇-dihydroxy-6, 7-methylenedioxyisoflavone （Ⅶ）; irisoid D （Ⅷ）; irisoid A（Ⅸ） and heptadecanoic acid （Ⅹ）. CONCLUSION： All the ten compounds were isolated from this plant for the first time and compound Ⅵ was isolated from genus Iris for the first time.

关 键 词：马蔺 黄酮类化合物 结构鉴定 化学成分 

分 类 号：R284[医药卫生—中药学]