浅裂鳞毛蕨中的一个新二苯乙烯苷(英文)  

A new stilbene glycoside from Dryopteris sublaeta

作　　者：冯卫生[1] 曹新伟[1] 匡海学[2] 郑晓珂[1] 

机构地区：[1]河南中医学院,河南郑州450008 [2]黑龙江中医药大学,黑龙江哈尔滨150040

出　　处：《药学学报》2005年第12期1131-1134,共4页Acta Pharmaceutica Sinica

基　　金：SupportedbytheKeyProjectofChineseMinistryofEducation(2003078)

摘　　要：目的研究浅裂鳞毛蕨(Dryopteris sublaetaCh ing et Hsu)的化学成分。方法利用D iaion HP-20,ToyopearlHW-40,Sephadex LH-20,硅胶柱等色谱技术进行分离纯化,根据化合物的理化性质和光谱数据鉴定结构。结果从浅裂鳞毛蕨中分离并鉴定了4个化合物,分别为:3,5-二羟基-二苯乙烯-3-O-新橙皮糖苷(1),3,5-二羟基-二苯乙烯-3-O-β-D-葡糖苷(2),白藜芦醇葡糖苷(3)和3,5,4′-三羟基-二苯乙基-3-O-β-D-葡糖苷(4)。结论化合物1为新化合物,其余化合物均为首次从该属植物中分离得到。Aim To study the chemical constituents of Dryopteris sublaeta Ching et Hsu. Methods Fresh plant of Dryopteris sublaeta Ching et Hsu was extracted twice with boiling water, concentrated to small volume under reduced pressure at 50 ℃. The concentrated material was partitioned with ether, ethyl acetate, and n-butanol. The fraction of ethyl acetate extract was chromatographed over macroporous adsorption resin （Diaion HP-20） eluted with a mixture of H2O and MeOH in increasing MeOH content.Their fractions from resin were repeatedly chromatographed over Toyopearl HW-40, Sephadex LH-20 and silica gel column chromatography. The compounds were identified on the basis of their physiochemical and spectral data. Results Four compounds were obtained and identified as 3,5-dihydroxy-stilbene-3-O-neohesperidoside （ 1 ）, 3,5-dihydroxy-stilbene-3-O-β-D-glucoside （ 2 ）, polydotin peceid （3） and 3,5,4＇-trihydroxy-bibenzyl-3-O-β-D-glucoside （4）. Conclusion Compound 1 is a new compound, the others were isolated from Dryopteris for the first time.

关 键 词：浅裂鳞毛蕨 鳞毛蕨属 二苯乙烯苷 3 5-二羟基-二苯乙烯-3-O-新橙皮糖苷 

分 类 号：R284.1[医药卫生—中药学] R284.2[医药卫生—中医学]