COPD合并阻塞性睡眠呼吸低通气综合症的临床研究  

The clinical study of COPD combined obstructive sleep apnea-hypopnea syndrome

作　　者：严峻海[1] 顾学章[1] 龚燕[1] 

机构地区：[1]上海第二医科大学瑞金医院卢湾分院,200020

出　　处：《临床肺科杂志》2006年第1期33-34,共2页Journal of Clinical Pulmonary Medicine

摘　　要：目的研究慢性阻塞性肺疾病(COPD)合并阻塞性睡眠呼吸低通气综合症(O SAHS)对肺功能、血氧饱和度(SaO2)、肺动脉压力的影响。方法对24例COPD和18例重叠综合征患者的肺功能、血氧饱和度、睡眠呼吸暂停低通气指数(AH I)、体重指数(BM I)进行比较。结果重叠综合征组与COPD组的夜间最低SaO2有显著性差异(P<0.05),AH I有显著性差异(P<0.01)。结论重叠综合征夜间缺氧往往比单纯的COPD更为明显。应该早诊断,早治疗,减少并发症。Objective To study the effect of COPD combined obstructive sleep apnea-hypopnea syndrome on pulmonary function, blood O2 saturation, and pulmonary arterial pressure. Methods Comparisions were made in function, oxygen saturation （SaO2）, apnea-hypopnea index （AHI）, body-mass index （BMI） between 24 COPD patients and 18 patients with overlap syndrome. Results The lowest SaO2 in night and AHI of the two groups were significantly different （P〈0.05）. Conclusion The patients with overlap syndrome experienced more severity anoxia in night than COPD patients. Early diagnose and treatment can decrease complication.

关 键 词：慢性阻塞性肺疾病 阻塞性睡眠呼吸低通气综合症 重叠综合征 

分 类 号：R563.9[医药卫生—呼吸系统]