麻桂解表颗粒的退热作用的实验研究  

Experimental Study on Antipyretic Effect of Magui Jiebiao Granule

作　　者：刘希飒[1] 吴林彬 冯玛莉[1] 裴小静[1] 

机构地区：[1]山西省中医药研究院,山西太原030012 [2]山西省食品药品监督管理局,山西太原030021

出　　处：《山西中医学院学报》2005年第4期8-9,共2页Journal of Shanxi College of Traditional Chinese Medicine

基　　金：山西省卫生厅科技发展计划资助项目(项目编号:041048-3)

摘　　要：目的:观察麻桂解表颗粒的退热作用。方法:用2,4-二硝基苯酚和大肠杆菌内毒素分别制成发热大鼠模型各40只。每种模型分为5组,每组8只,分别给予生理盐水,阿斯匹林和麻桂解表颗粒低、中、高剂量,记录发热大鼠不同时间的体温。结果:麻桂解表颗粒低、中、高剂量均可显著降低发热大鼠模型的体温。结论:麻桂解表颗粒对化学性致热、内毒素致热大鼠均有明显退热作用,随剂量增加,起效时间缩短。Objective： T0 explore the antipyretic effect of Magui Jiebiao Granule（MJC）,Methods：The febrile model rats were induced by 2,4-dinitrophenol（model 1）and coleoceles＇ endotoxi（model 2）,Model 1（n=40）and model 2（n=40）respectively were randomized into five groups（n=8）,Then five groups were ig with normal saline,70mg/kg of aspirin and 1.0g/kg,2.0g/kg,4.0g/kg of MJG.The rats＇temperatures were recorded.Results：MJG can decrease the temperature of the febrile rats .Comclusion：MJG has significant antipyretic effect,which relate with the dosage.

关 键 词：麻桂解表颗粒 大肠杆菌内毒素 2 4-二硝基苯酚 退热 

分 类 号：R285[医药卫生—中药学]