烫伤紫油膏质量标准的研究  

Studies on the quality standard of Tanshangzi ointment

作　　者：杨学猛[1] 罗桂萍[1] 徐凤梅[1] 

机构地区：[1]天津市第三中心医院,天津300170

出　　处：《天津药学》2005年第6期14-16,共3页Tianjin Pharmacy

摘　　要：目的:建立烫伤紫油膏的质量控制方法.方法:采用碱提取-酸沉淀的方法提取左旋紫草素.以薄层色谱法进行定性鉴别.运用可见分光光度法进行含量测定.结果:左旋紫草素在5～25 μg/ml范围内呈良好线性关系(r=0.999 9),平均回收率为100.3%,RSD=1.15%.结论:本方法简便准确,重复性好,适用于该制剂的质量控制.Object： To establish a method for the quality control of Tangshangzi ointment. Methods： Shikonin was extracted by alkali extraction-acid precipitation and identified by TLC. Its content was determined by spectrophotometry. Results： A linear relationship was obtained for shikonin over the range of 5 - 25 μg/ml（ r = 0.999 9）. The average recovery was 100.3 % with RSD of 1.15 %. Conclusion： The method was simple, sensitive and accurate. It can be used for the quality control of Tanshangzi ointment.

关 键 词：烫伤紫油膏 紫草 薄层色谱法 可见分光光度法 

分 类 号：R943[医药卫生—药剂学]