右心腔声学造影及定量组织速度成像评价犬右心收缩功能  

Quantitative Assessment of Right Ventricular Systolic Function by Time-intensity Curve with Right Ventricular Contrast and Quantitative Tissue Velocity Imaging

作　　者：王林[1] 邓又斌[1] 李天亮[1] 杨好意[1] 常青[1] 毕小军[1] 向慧娟[1] 黎春雷[1] 

机构地区：[1]华中科技大学同济医学院附属同济医院超声影像科,武汉430030

出　　处：《放射学实践》2005年第12期1084-1086,共3页Radiologic Practice

摘　　要：目的:探讨心腔声学造影时间-强度曲线(TIC)各项参数及三尖瓣定量组织速度成像(QTVI)参数定量评价右心收缩功能的价值。方法:对10只犬分别在基础状态及注射心得安后心功能减退状态下经股静脉重复注射5%声振白蛋白注射液,剂量0.08 ml/kg。于心尖四腔切面观察右心室对比剂的充盈及清除,采用拟合曲线定量分析方法获取心腔声学造影TIC各项参数,并分析各项参数在不同的心功能水平的差异。应用多普勒超声心动图分别在基础状态及注射心得安后心功能减退状态下记录三尖瓣环组织多普勒图像,测量三尖瓣环收缩期运动速度(Vs)。结果:随心功能的减退,TIC各项参数中时间常数(k)明显减小,而对比剂峰值强度减半时间(HT)及对比剂平均通过时间(MTT)明显延长,三尖瓣环收缩期运动速度(Vs)明显减慢(P<0.001),k与Vs呈明显正相关(r=0.71)。结论:右心腔声学造影TIC参数与QTVI参数在定量评估右心收缩功能时具有重要价值。Objective：To detect the value of parameters of time intensity curve （TIC） with ventricular contrast and quantitative tissue velocity imaging （QTVI） in the quantitative assessment of right ventrieular systolic function. Methods： 5% sonicated human albumin was injected intravenously in does of 0.08ml/kg at baseline and decrease of cardiac function after injection of propranolol in 10 dogs. Four chamber view was observed for wash in and wash out of contrast agent from right ventricle. The parameters of TIC were obtained by curve fitting. Tricuspid annulus systolic velocities （Vs） were measured by quantitative tissue velocity imaging. Results： Among the parameters derived from TIC,the time constant （k） stepped down significantly with decrease of cardiac function （P〈0.001）,but half time of decent of peak intensity and mean transit time of wash-out extended significantly （P〈0.001）. Among the data derived from QTVI,the V, stepped down significantly with decrease of cardiac function （ P〈0.001 ）. The k was strongly related with Vs （ r=0.71, P〈0.001 ）. Conclusion ： There is significant value of the parameters derived from TIC with right ventricular contrast and Vs from QTVI in the quantitative assesment of right ventricular systolic function.

关 键 词：心室功能 右 超声心动描记术 超声检查 多普勒 彩色 

分 类 号：R445.1[医药卫生—影像医学与核医学]