抗癫痫药物研究进展  

Progresses in studies on anti-epileptic drugs

作　　者：洪钢 章江生 王琳辉[3] 

机构地区：[1]江苏省药品认证管理中心 [2]康恩贝集团有限公司 [3]苏州大学医学院生理学教研室

出　　处：《中国临床药理学与治疗学》2005年第11期1201-1209,共9页Chinese Journal of Clinical Pharmacology and Therapeutics

摘　　要：癫痫是一种由多种不同原因引起的严重脑部疾病,随着对癫痫发病机理研究的深入,更多的抗癫痫药物得以开发使用。本文分类综述了γ氨基丁酸(GABA)能药物、谷氨酸受体拮抗剂以及作用于膜离子通道、神经肽受体等靶点的抗癫痫新药。Epilepsy is a common serious brain disorder and comprises a wide range of symptom induced by varying etiologies. As more and more knowledge of mech- anisms underlying seizure propagation of epilepsy gained, much more new antiepileptic-drug has been developed. Inthis article, we reviewed some kinds of new antiepileptic drugs used or researched in recent years.

关 键 词：癫痫 Γ-氨基丁酸受体 谷氨酸受体 离子通道 神经肽 

分 类 号：R971.4[医药卫生—药品]