心肌造影超声心动图定量分析软件系统的设计与实现  

Design of a Quantitative Analysis Software System for Myocardial Contrast Echocardiography

作　　者：孙丰荣[1] 张明强[1] 姚桂华[2] 宋好好[1] 刘利[1] 张运[2] 

机构地区：[1]山东大学信息科学与工程学院,济南250100 [2]山东大学齐鲁医院,济南250012

出　　处：《生物医学工程学杂志》2005年第6期1095-1099,共5页Journal of Biomedical Engineering

基　　金：国家自然科学基金资助项目(60072022)

摘　　要：心肌声学造影是当前超声心动图学的国际研究热点。本文设计的心肌造影超声心动图(M CE)定量分析软件系统,通过非线性回归分析方法计算出正常、缺血、梗死、存活心肌区域内微血管血流量、血容量、血流分布和血流储备等冠状动脉微循环血流动力学临床诊断指标,从而使M CE上升到定量评价心肌灌注的新水平。本文软件系统的设计完全遵从D ICOM国际标准,可无缝接入PACS系统。This article reports a quantitative analysis software system for myocardial contrast echocardiography （MCE）. It can measure the signal intensity of grayscale images and power Doppler images, draw the time-lntensity curves of variations on the intensity of microbubbles scattering in subendocardial layer and subepicardial layer with the pulsing intervals, and estimate the hemodynamic parameters by nonlinear regression analysis. This system has been applied to a study on 20 healthy volunteers, and the results suggest that the software has the capacity for bringing the quantitative analysis of MCE to success. The MCE software system conforms to the DICOM standard and can be integrated into PACS.

关 键 词：心肌造影超声心动图 定量诊断 非线性回归分析 

分 类 号：TH789[机械工程—仪器科学与技术]