慢性荨麻疹患者血清白三烯B4的检测  

Investigation on the Serum Leukotriene B4 in Patients with Chronic Urticaria

作　　者：黎志刚[1] 曾仁山[1] 王瑞善[1] 杨捷[1] 吴江[1] 

机构地区：[1]广东省广州市第一人民医院皮肤科,广东广州510180

出　　处：《岭南皮肤性病科杂志》2005年第4期285-286,共2页Southern China Journal of Dermato-Venereology

摘　　要：目的:探讨慢性荨麻疹患者血清白三烯B4的改变与发病的关系。方法:采用酶联免疫法对65例慢性荨麻疹患者血清白三烯B4进行测定,并以42例健康正常人作为对照。结果:研究组血清白三烯B4水平明显高于对照组(P<0.05)。结论:慢性荨麻疹患者的发病与血清白三烯B4水平有关,在对其常规抗组胺治疗的同时,抗白三烯B4的治疗可提高疗效。Objective：To investigate the relationship between serum leukotriene B4 and the development of chronic urticaria. Methods： Plasma level of leukotriene B4 in 65 patients with chronic urticaria and 42 healthy controls were detected by enzyme immunoassay method. Results：The results showed that plasma level of leukotriene B4 in 65 patients with chronic urticaria was significantly higher than that of normal controls. There was statistical difference in two groups. Conclusion ： It was suggested that leukotriene B4 plays an important role in the pathogenesis of chronic urticaria.

关 键 词：慢性荨麻疹 白三烯B4 

分 类 号：R758.24[医药卫生—皮肤病学与性病学]