婴幼儿轮状病毒性肠炎与母乳喂养的相关性研究  

Study on the Relationship Between Infant Rotavirus Enteritis and Breast Feeding

作　　者：陈艳萍[1] 魏涛[2] 刘慧[1] 孙雪荣[1] 王斌[3] 

机构地区：[1]青岛市妇女儿童医疗保健中心 [2]青岛市市立医院,266011 [3]青岛大学医学院病原生物学教研室

出　　处：《放射免疫学杂志》2005年第6期503-505,共3页Journal of Radioimmanology

摘　　要：目的:探讨轮状病毒性肠炎与母乳喂养的相关性,及母乳喂养在各不同年龄分组中的作用;讨论携带A组轮状病毒的母体母乳喂养潜在的危险.方法:选用胶体金方法作为筛查实验,所有阳性标本再用RTPCR方法检测确认.结果:在青岛地区的婴幼儿腹泻中,轮状病毒性肠炎的发病率为31.2%;其中母乳喂养阳性率为26.8%,明显低于人工喂养组45.2%;母乳喂养在(0～6)个月和(7～12)个月年龄段的感染率均明显低于非母乳喂养组.在母乳喂养组中,母乳轮状病毒阳性的患儿其粪便轮状病毒总的阳性率明显高于母乳轮状病毒阴性组的乳儿.结论:(1)母乳喂养在婴幼儿轮状病毒性腹泻的病毒感染中具有重要的保护作用;(2)母乳在给婴幼儿提供必需的营养成分和保护性物质的同时也传播着一些危害因素.Objective To study the relationship between infant rotavirus enteritis and breast feeding, with emphasis on early immuno - protection provided by breast feeding as well as later possible hazards with rotavirus carrier mothers. Methods Stool specimens from 520 infants with diarrhea were screened for rotavirus with colloid gold method. Positive specimens were confirmed with RTPCR. Results In local （Qingdao） infants with enteritis, the over- all incidence of rotovirus infection was 31.2%. Positive rate in breast -feeding infants was only 26.8%, being significantly lower than that in bottle - feeding ones （45.2%）. The virus infectivity rate in both groups of breast - feeding infants （below 6 months and 7 - 12 months） was lower than the corresponding rate in the bottle feeding group. However, infant fed from rotavirus carriers had significantly higher fecal positive rate of rotovirus than that in infants fed from non - carriers. Conclusion ①At beginning, espeially below 6 months, breast - feeding provided important protection again rotovirus enteritis in the infants. ②certain infections could be transmitted through breast feedings, which deserved closer observation.

关 键 词：轮状病毒 母乳喂养 轮状病毒抗原 RT-PCR 婴幼儿 

分 类 号：R512.5[医药卫生—内科学] R174.4[医药卫生—临床医学]