桥本氏病诊断与治疗中甲状腺激素及自身抗体的变化规律  

The Changing Pattern of Thyroid Hormone and Autoantibodies in the Diagnosis and Treatment of Patients with Hashimoto's Thyroiditis

作　　者：张永学[1] 叶维新[2] 曹国祥[1] 熊洁[1] 安锐[1] 陈格[2] 曾腊玲[1] 徐文代[1] 袁斌[1] 

机构地区：[1]同济医科大学附属协和医院核医学科 [2]同济医科大学实验医学研究中心核医学研究室

出　　处：《同济医科大学学报》1989年第A01期50-52,共3页Acta Universitatis Medicinae Tongji

摘　　要：本文对115例桥本氏病作了分析,其中甲状腺功能亢进者30例,功能正常者52例,功能减低33例,TG-Ab和TM-Ab阳性率分别为87.5％和81.3％。本文对23例患者进行了2～24个月动态观察,无论是甲亢或是甲低者,在抗甲状腺药物或替代治疗中,甲状腺激素浓度变化对治疗较敏感,短期内可恢复正常,自身抗体转阴则较缓慢。This paper presents an analysis of 115 cases of Hashimoto's thyroi-ditis, among whom 30 were diagnosed as hyperthyroid, 52 as euthyroid and 33 as hypothyroid respectively. Tg-Ab and Tm-Ab were positive in 87.3 % and 81.7 % cases respectively. Dynamic observations were made in 23 cases of Hashimoto's thyroiditis during 2-24 months. In the case of hyperthyroid or hypothyroid, whether treated by anti-thyroid drugs or by thyroxine displacement, the concentration changes of thyroid hormone was relatively sensitive, but the autoantibody normalization was rather slow.

关 键 词：桥本氏病 甲状腺激素 诊断 

分 类 号：R581.404[医药卫生—内分泌]