原子荧光光度法测定常通口服液中重金属砷的含量  

Determination of Heavy Metal Element,Arsenic,in Changtong Oral Liquid with Atomic Fluorometry

作　　者：郭丹[1] 陈娜娜[2] 杨西晓[1] 侯连兵[1] 

机构地区：[1]南方医科大学南方医院药学部,广州510515 [2]南方医科大学药物研究所,广州510515

出　　处：《医药导报》2006年第1期59-60,共2页Herald of Medicine

基　　金：国家新药研究基金资助项目(基金编号:96-901-05-245)

摘　　要：目的测定中药常通口服液中重金属砷（As）的含量。方法采用原子荧光光度法，负高压300V，光源用砷空心阴极灯，灯电流为60mA，原子化器高度8．0mm，载气流量300mL·min^-1，屏蔽气流量700mL·min^-1。结果重金属砷在0．4-25．6ng·mL^-1浓度范围内线性关系良好，r=0．9997，平均回收率为98．27％，RSD=2．83％（n=5）。结论该法简单、快速、灵敏，常通口服液中重金属砷含量符合规定。ABSTRACT Objective To delermine the content of the heavy metal element, As,in changtong oral liquid. Methods Atomic fluorometry was used under the condition of PNT voltage of 300 V, lamp current of 60 mA, carry gas flow rate of 300 mL ·min^-1 , and shield gas flow rate of 700 mL ·min^-1. Results The calibration curves was linear in the range of 0.4 - 25.6 ng·min^-1 for the heavy metal element, As （ r = 0. 999 7 ）. The average recovery of the heavy metal element, As, was 98.27% （ n = 5 ,RSD = 2.83% ）. Conclusion This method is simple, quick and sensitive . The content of As in changtong oral liquid accords with the standard.

关 键 词：常通口服液 砷 重金属 原子荧光光度法 

分 类 号：R286[医药卫生—中药学] R927.2[医药卫生—中医学]