糖化血红蛋白测定在妊娠糖尿病诊断中的临床意义  

Investigation of clinical value of glycosylated hemoglobin test in diagnosing gestational diabetes mellitus.

作　　者：李继红[1] 陈晓薇[1] 朱锋[1] 

机构地区：[1]广东省珠海市妇幼保健院,519000

出　　处：《中国妇幼保健》2006年第1期111-113,共3页Maternal and Child Health Care of China

摘　　要：目的:探讨糖化血红蛋白在妊娠糖尿病诊断中的临床意义。方法:对正常妊娠组60例、糖耐量异常组60例及糖尿病组56例等血清进行FPG、口腹50g葡萄糖筛选实验和HbAIc的测定。结果:HbA lc的阳性率在正常妊娠组、糖耐量异常组和GDM组中分别为3.33%、25%和80.4%,GDM组与正常妊娠组和糖耐量异常组相比均有显著性差异(P<0.05),空腹血糖阳性率在三组中分别为8.33%、10%和37.5%,糖筛查实验阳性率在三组中分别为20%、20%和83.9%,妊娠糖尿病的并发症随HbAIc的增高而增多。结论:HbAIc在妊娠糖尿病诊断和监测中具有重要意义。Objective： To explore the clinical value of glycosylated hemoglobin test in diagnosing gestational diabetes mellitus. Methods. To measure the fasting blood sugar, oral glucose 50 g screen and HbAIc for 60 cases in normal pregnancy women group, 60 ones in impaired glucose tolerance group and 56 ones in gestational diabetes mellitus group. Results： The positive rate of HbAIc in normal pregnancy women group, impaired glucose tolerance group and gestational diabetes mellitus group were 3. 33% , 25% and 80. 4% respectively, the difference between normal pregnancy women group and impaired glucose tolerance group was significant （ P 〈 0. 05 ） , the difference between normal pregnancy women group and gestational diabetes mellitus group was also significant （ P 〈 0. 05 ） , the positive rate of the fasting blood sugar in the above three groups were 8. 33% , 10. 0% and 37. 5% respectively, the positive rate of oral glucose 50 g screen in the above three groups were 20% , 20% and 83. 9% respectively. The incidence of complication of gestational diabetes mellitus increased when the level of HbAIc was high. Conclusion： It is a significant value that glycosylated hemoglobin can be used to diagnose and detect gestational diabetes mellitus.

关 键 词：糖化血红蛋白 妊娠糖尿病 临床 

分 类 号：R714.256[医药卫生—妇产科学]