冠心病不稳定性斑块的临床研究  

Unstable plaques in coronary heart disease

作　　者：梁波[1] 王艳霞[1] 张迎春[1] 

机构地区：[1]齐齐哈尔医学院第二附属医院心内科

出　　处：《中国心血管病研究》2006年第1期34-35,共2页Chinese Journal of Cardiovascular Research

基　　金：齐齐哈尔医学院指导科研项目(XY2003-31-27)

摘　　要：目的探讨血清中可溶性细胞间黏附分子-1(ICAM-1)与动脉粥样斑块稳定性的关系。方法测定急性冠状动脉综合征(ACS)患者在入院即刻、入院1周、出院时的血清ICAM-1浓度,并与对照组比较分析。结果ACS组血清ICAM-1浓度明显高于对照组,且差异有统计学意义(P<0.05)。结论ICAM-1与冠脉斑块不稳定性呈密切相关,可望作为诊断冠脉斑块不稳定性的参考指标。Objective To investigate the relationship between ICAM-land the stability of plaques. Methods Plasma levels of ICAM-lwere tested in patients with acute coronary syndrome at hospitalization, one week later and at discharge. Results The plasma level of ICAM-1 was much higher in vulnerable plaque group than in stable plaque group （P〈0.05）. Conclusion ICAM-1 may be involved in the pathogenesis of ACS and relate to the unstability of plaques.

关 键 词：冠状动脉疾病 斑块切除术 冠心病 不稳定性斑块 

分 类 号：R541.4[医药卫生—心血管疾病]