刺五加注射液对小鼠实验性急性心肌缺氧的保护作用  

Protective effect of acanthopanax senticosus injection on the acute myocardial anoxia in mice

作　　者：马锐[1] 徐欢[1] 杨丽丽[1] 程亮[1] 唐云国[1] 叶云[1] 

机构地区：[1]蚌埠医学院医学系,2001年级安徽蚌埠233030

出　　处：《蚌埠医学院学报》2006年第1期17-19,共3页Journal of Bengbu Medical College

摘　　要：目的:观察刺五加对小鼠急性心肌缺氧的保护作用。方法:常压缺氧条件下分别观察小鼠平均存活时间和心肌耗氧量;采用夹闭气管法观察小鼠平均心电消失时间。结果:刺五加注射液高、低剂量组均能延长小鼠平均存活时间,降低心肌耗氧量。结论:刺五加注射液能明显降低小鼠心肌氧耗,保护缺氧心肌,延长小鼠存活时间。Objective：To observe the role of acanthopanax senticosus injection in the protection of acute myocardial anoxia in mice. Methods：The mean survival time and the capacity of myocardial oxygen consumption under ordinary pressure in mice were observed and the disappearance time of electrocardiographic sign in mice was measured by clamping their trache. Results： Acanthopanax senticosus injection of various dosages could prolong the mean survival time and decrease the disappearance time of electrocardiographic sign in mice. Conclusions： Acanthopanax senticosus injection can evidently reduce the capacity of myocardial oxygen consumption, protect the hypoxic myocardium and increase the ability of anti-stress in mice with acute myocardial anoxia.

关 键 词：心肌疾病 刺五加 药理学 小鼠 

分 类 号：R542.2[医药卫生—心血管疾病] R282.71[医药卫生—内科学]