青银注射液中总绿原酸的紫外含量测定  

DETERMINATION OF THE CONTENT OF TOTAL CHLOROGENIC ACID IN QING YING INJECTION BY ULTRAVIOLET SPECTROPHOTOMETRY

作　　者：何兵[1] 王琳[2] 田吉[1] 冯文宇[1] 邱华荣[1] 

机构地区：[1]泸州医学院药学院药研所,四川泸州646000 [2]泸州医学院药学教研室,四川泸州646000

出　　处：《泸州医学院学报》2005年第6期497-499,共3页Journal of Luzhou Medical College

基　　金："九五"国家科技攻关项目(96-901-05-020)

摘　　要：目的测定青银注射液中总绿原酸的含量。方法采用紫外分光光度法在324nm处测定吸收度,并用绿原酸的吸收系数计算其含量。结果青银注射液中总绿原酸的平均含量为19.38mg/ml。结论该法操作简便快速,稳定性,精密度,重现性和回收率均较好,可用于青银注射液生产过程中的质量控制。Objective： To determine the content of total chlorogenic acid in Qingying injection. Methods： Ultraviolet spectrophotometry was employed to determine the absorbance at wavelength 324nm. Then the content was calculated by absorption coefficient of chlorogenic acid. Results： The average content of total chlorogenic acid is 19.38 mg/ml.Conclusion： This method is simple, rapid, and stable, with good precision, reproducibility, and recovery. It can be used for quality control in production process of Qingying injection.

关 键 词：青银注射液 总绿原酸 分光光度法 含量测定 

分 类 号：R917[医药卫生—药物分析学]