2-羟基-3-烯丙氧基丙磺酸钠的合成  

Synthesis of 3-Allyloxy-2-hydroxy-1-propanesulfonic Acid Salt

作　　者：王克乐[1] 朱红军[1] 王锦堂[1] 

机构地区：[1]南京工业大学理学院应化系,江苏南京210009

出　　处：《江苏化工》2005年第6期43-44,共2页Jiangsu Chemical Industry

摘　　要：采用新方法合成了2-羟基-3-烯丙氧基丙磺酸钠。先由环氧氯丙烷和亚硫酸氢钠合成中间体3-氯-2-羟基丙磺酸钠,然后中间体再与丙烯醇在氢氧化钠催化下生成目标产物2-羟基-3-烯丙氧基丙磺酸钠。2步反应总收率在70%左右,中间体和产物分别进行了光谱表征。A new process on the synthesis of 3 - allyloxy - 2 - hydroxy - 1 - propanesulfonic acid salt is reported here. At first, the intermediate of sodium 3 - chloro - 2 - hydroxy propanesulfate was synthesized from epichlorohydrin and sodium bisulfite; And then, using NaOH as a catalyst, the title compound has been synthesized from intermediate and allyl alcohol to reach the yield of about 70%. The structure and component of the product was verified by IR, NMR and elecment analysis.

关 键 词：环氧氯丙烷 丙烯醇 2-羟基-3-烯丙氧基丙磺酸钠 

分 类 号：TQ227.42[化学工程—有机化工]