次声环境对船员部分血液指标的影响  

Effects of infrasound on blood indices of warship crewmen

作　　者：郭丰涛[1] 梁振福[1] 黄锋[1] 史蕾[1] 

机构地区：[1]海军医学研究所,上海200433

出　　处：《中华航海医学与高气压医学杂志》2005年第4期211-214,共4页Chinese Journal of Nautical Medicine and Hyperbaric Medicine

摘　　要：目的探讨次声对船员某些生理生化功能的影响.方法两艘同类型船分为试验船(试验组)和对照船(对照组).两船同时出航,同时返航,试验时同时关闭主机.试验船的次声装置连续工作6 h,船上主要舱室和工作位置的次声级为105.0～117.0 dB,其频谱能量12.5～20.0 Hz.对照船未启动次声装置,其它条件与试验船基本相同.试验前后采集两组船员血样,检测血清免疫指标3项,血浆和溶血液生化指标11项.结果经连续6 h次声环境暴露后,试验组船员血清IgG测得值为(13.99±1.73)g/L,比航前测得值( 13.27±1.61) g/L增加(P＜0.01),也较对照组航后测得值(13.75±2.94) g/L增加(P＜0.05).试验组船员血浆GSH(还原型谷胱甘肽)测定值为(272.08±39.10) mg/L,比航前测定值(231.18±25.39) mg/L增加17.69%(P＜0.01),而对照组航后增加12.42%.航行作业后,试验组RBC-ChE和T-LDH分别比航前升高236.6%和122.6%,而对照组无大的变化,可能与次声环境有关.另外,两组红细胞Ca2+-ATPase和血清T-AOC也比航行作业前有明显下降(P＜0.05和P＜0.01).其它指标的变化,大多在正常参考值范围.结论在本研究条件下,船员部分血液指标如RBC-ChE,T-LDH和GSH出现明显的变化,可能与次声作用有关.Objective To investigate the influence of infrasourd on some physioIogical functions in crewmen. Methods Two ships of the same type, named experimental group ship and control group ship, went on voyage. The infrasound-generator on the experimental ship worked continuously for 6 h and the levels of infrasound in most cabins or work stations were 105 - 117 dB with the main frequency-spectrum energy at 12.5, 16,and 20.0 Hz. On the control ship, the i nfrasound-generator was shutted off and was kept in safe distance from the experimental ship for 6 h. The blood samples were collected from all the crewmen in both ships before and after the experiment, and 3 immune and 11 biochemical indices were examined. Results After continuous exposure to infrasound for 6 h,the content of plasma IgG in the experimental crewmen （13.9 ± 1.7 g/L） was increased significantly compared with that before exposure（ 13.3 ± 1.6 g/L） （P 〈 0.01 ）. It also increased significantly compared with that of the control group after voyage（ 13.8 ± 2.9 g/L） （ P 〈 0.05 ）. Similarly, the values of plasma GSH of the experimental group was increased by 17.69% after voyage （ P 〈 0.01 ） （272.08 ± 39.10 mg/L vs 231. 18±25.39 mg/L） ,and in the control group that value was increased by 12.42%. The values of plasma RBC-ChE and T-LDH of the experimental group were increased by 236.6% and 122.6% , respectively（ RBC-ChE 4.09 ± 1.92 μmol/mgHb vs 1.22±0.36μmol/mgHb,T-LDH 4796±229 U/L vs 2155 ± 514 U/L） ,but no notable changes of these values were seen in the control group after voyage. In addition, Ca^2＋ -ATPase in RBC and T-AOC in serum in both groups were decreased notably after voyage. Conclusions Some notable changes occurred in some blood indices such as RBC-ChE,GSH and T-LDH in the experimental group after voyage,which may be related to infrasound environment.

关 键 词：次声 次声环境暴露 免疫指标 血液指标 

分 类 号：R83[医药卫生—航空、航天与航海医学]