四川彝族的起源初探——来自人类白细胞抗原-B基因的线索  

The Origin of Sichuan Yi Ethnic Group Inferred by Human Leukocyte Antigen-B Gene Study

作　　者：许铭炎[1] 陈耿臻[2] 李军[1] 陈子平 傅玉才[1] 

机构地区：[1]汕头大学医学院病原生物学教研室 [2]汕头大学医学院第一附属医院普外科,广东汕头515041 [3]诏安县医院,福建诏安363500

出　　处：《汕头大学医学院学报》2005年第4期234-237,共4页Journal of Shantou University Medical College

摘　　要：目的:根据人类白细胞抗原(HLA)-B基因频率,探讨四川彝族的民族起源。方法:收集四川彝族群体的HLA-B基因频率和已报道国内其他主要民族人群的HLA-B基因数据,运用PHYLIP对HLA-B数据进行聚类分析,主成分分析由SPSS11.0完成。结果:从聚类树型结构图可知,我国主要民族明显分为南北两大群,四川彝族虽处于北方人群一组,但在遗传距离上介于南北方人群之间。主成分分析发现,彝族处于汉藏语系群体之中,与藏族群体关系最近。结论:从HLA-B基因的角度分析,四川彝族的HLA-B遗传特征表现为源于北方,与藏族关系密切。Objective： To study the origin of Sichuan Yi ethnic group according to human leukocyte antigen（ HLA）-B gene frequency. Methods： HLA-B gene frequencies of Yi ethnic group and other related Chinese ethnic groups were collected. Cluster analysis and principle component analysis were performed by PHYLIP software and SPSS11.0 respectively. Results： From the phylogenetic tree formed by cluster analysis, mainly Chinese ethnic groups could be divided into Southern and Northern population. Although Sichuan Yi ethnic group was clustered with the Northern population, the genetic distance was between Southern and Northern population. By principle component analysis, Yi ethnic group showed close to Tibetan in the Han-Tibet speaking population. Conclusion： From the clue of HLA-B gene, Yi ethnic group shows the genetic characteristic of Northern Chinese and has a close relationship with Tibetan.

关 键 词：四川彝族 人类白细胞抗原-B 基因频率 聚类分析 主成分分析 

分 类 号：Q347[生物学—遗传学]