多囊卵巢综合征患者血清瘦素、IGF-Ⅰ水平的研究  

On the serum leptin and IGF-Ⅰ levels in patients with polycystic ovary syndrome

作　　者：范林霄[1] 郝敏[1] 杨燕生[1] 

机构地区：[1]山西医科大学第二附属医院妇产科

出　　处：《中华内分泌代谢杂志》2005年第6期541-542,共2页Chinese Journal of Endocrinology and Metabolism

基　　金：山西省自然科学基金项目(20021116)

摘　　要：测定36例多囊卵巢综合征(PCOS)患者和26名对照个体血清瘦素、胰岛素样生长因子(IGF)Ⅰ、IGF结合蛋白1(IGFBP1)、空腹胰岛素(FINS)的水平,结果显示PCOS组血清瘦素、IGF-Ⅰ、FINS水平高于对照组,IGFBP1低于对照组。PCOS患者血清瘦素水平与FINS呈正相关。Serum levels of leptin, insulin-llke growth factor （IGF） Ⅰ , IGF binding protein-1 （ IGFBP1 ）, fasting insulin （FINS） were determined in 36 patients with polycystic ovary syndrome （PCOS） and 26 control subjects. The results showed that serum leptin, IGF- Ⅰ , FINS in PCOS patients were significantly higher than those in control subjects, and serum IGFBP1 level was significantly lower than that in control subjects. Serum leptin was positively correlated with FINS in PCOS patients.

关 键 词：多囊卵巢综合征 瘦素 胰岛素样生长因子Ⅰ 胰岛素样生长因子结合蛋白1 

分 类 号：R711.75[医药卫生—妇产科学]