消痞灵冲剂对实验性胃癌前期病变大鼠血液流变学的影响  

Effects of xiaopiling chongji on Hemorheology of experimental gastric precancerous lesion in rats

作　　者：张旭晨[1] 赵凤志 宋崇顺 代欣 任映 田德录 董建华 

机构地区：[1]河北省承德医学院病理教研室,承德市067000 [2]北京中医药大学东直门医院

出　　处：《新消化病学杂志》1996年第4期208-210,共3页

摘　　要：目的观察胃癌前期病变大鼠血液流变学的变化和消痞灵冲剂的影响。方法制备大鼠胃癌前期病变模型,并应用消痞灵冲剂对其进行防治。实验结束后,测定血液流变学变化。结果病变组大鼠存在血液流变学异常,大、中剂量的消痞灵冲剂对其异常存改善作用。结论血液流变学异常参与了胃癌前期病变的发生和发展,改善其异常为消痞灵冲剂对病变发挥防治作用的机制之一。AIMS To study the changes of Hemorheology in gastric precancerous lesion (GPL)in rats and effects of xiaopiling chongji(XPC)on that. METHODS Model of GPL was made and XPC was used to prevent and treat.The changes of Hemorheology were detected when experiment ended. RESULTS Abnormalities of Hemorheology were existed in pathological groups,and improved by using large and moderate doses of XPC. CONCLUSIONS Abnormalities of Hemorheology play some roles in the pathogenesis and progress of GPL.To improve the abnormalities might be one of mechanisms of XPC's preventive and therapeutic effects on GPL.

关 键 词：胃肿瘤 癌前病变 消痞灵冲剂 中药品 血液流变学 

分 类 号：R273.520.5[医药卫生—中西医结合] R286.91[医药卫生—中医肿瘤科]