烧伤病人休克期血浆ANP、BNP含量变化  

The Content Change of ANP and BNP in Burn Patients′Plasma during Shock Period

作　　者：赵英[1] 郭菲[1] 廖立新[1] 李国辉[1] 

机构地区：[1]南昌大学第一附属医院烧伤科,江西南昌330006

出　　处：《江西医学院学报》2005年第6期80-81,共2页Acta Academiae Medicinae Jiangxi

基　　金：江西省卫生厅科研基金资助项目;NO:20043037

摘　　要：目的观察烧伤病人休克期血浆中ANP(心钠素)、BNP(脑钠素)含量变化,探讨其临床意义。方法选取伤后8 h内入院的烧伤休克期住院病人14例,抽取病人静脉血3 mL,用放射免疫方法,检测ANP、BNP含量,并与正常成人作对照。结果烧伤患者休克期血浆中ANP、BNP含量明显高于正常成人,差异有显著性(P<0.01);随烧伤面积增大ANP、BNP含量增大,BNP比ANP变化更为明显(P<0.01)。结论烧伤后血浆中ANP、BNP含量明显上升;BNP含量的变化比ANP更敏感;休克期ANP、BNP含量的变化可能与容量失衡有关。Objective To observe the content change of plasma ANP,BNP in the patients with burn during shock period and discuss the clinical significance. Methods Fourteen patients with burning for eight hours and in shock period underwent the experiment. Three mL vein blood was taken to detect the content of ANP,BNP using radioimmunoassay method and compare with the data of normal adults. Results The content of ANP,BNP in patients with burn in shock period was obviously higher than that of normal group, which had very remarkable significance （P〈 0.01）. The ANP and BNP were higher with the burn surface increased（P〈0. 01）. Conclusion The content of ANP and BNP is rising obviously after burning and the content change of BNP is more sensitive than ANP. The content of ANP, BNP during shock period may have something with capacity balance.

关 键 词：心纳素 脑钠素 烧伤 休克 

分 类 号：R644[医药卫生—外科学]