2H-1,4-苯并噁嗪类化合物合成研究进展  

Progress in synthesis of 2H-1,4-benzoxazine derivates

作　　者：闵忠诚[1] 杨道武[2] 谌伟民[1] 张泉[1] 黄明智[1] 

机构地区：[1]华中师范大学,湖北武汉430079 [2]长沙理工大学化学与环境工程系,湖南长沙410077

出　　处：《精细化工中间体》2005年第6期7-10,共4页Fine Chemical Intermediates

基　　金：国家自然科学基金资助项目(20372021);湖南省自然科学基金资助项目(03JJY3018)

摘　　要：综述了不同取代基的2H-1,4-苯并噁嗪类化合物的合成方法。可以概括为两大类,其一以邻胺基苯酚或间卤苯酚为原料,与不同的-α卤代酸或酯反应,反应中不需要催化剂,在工业生产中普遍采用;另一类是用钯作催化剂,能扩大化合物的类型,并可选择性合成光学活性物质。Synthesis methods of 2H-1, 4-benzoxazine derivatives were reviewed in this paper. These methods could be classified into two classes： one was the reaction of o-aminophenol or m-halophenol with different α- halogenated acids or esters without any catalyst, which was Used widely in industrial production; the other could enlarge compoundsj classes via palladium as catalyst, and give optically active compound.

关 键 词：2H-1 4-苯并嗯嗪 合成 进展 

分 类 号：TQ254.19[化学工程—有机化工]