Dornir CPAP家庭用呼吸机治疗阻塞性睡眠呼吸暂停综合征的临床疗效  

The Effett of Dornir CPAP Home Ventilator on Treatment of Obstructive Sleep Apnea Syndrome

作　　者：李善群[1] 聂莉[1] 刘伟[1] 钮善福[1] 何礼贤[1] 白春学[1] 

机构地区：[1]复旦大学附属中山医院肺科中山医院睡眠呼吸障碍与鼾症诊治中心,上海200032

出　　处：《中国临床医学》2005年第6期1010-1011,共2页Chinese Journal of Clinical Medicine

摘　　要：目的:观察持续正压通气(CPAP)对阻塞性睡眠呼吸暂停综合征(OSAS)的治疗效果,并结合应用体会提出临床注意事项。方法:应用CPAP呼吸机治疗30例OSAS患者,并使用夜间多导睡眠图判断CPAP治疗OSAS的效果。结果:CPAP治疗压力为6- 12 cmH2O,平均治疗压力10．5±3．4 cmH2O。治疗后患者的各种临床不适基本缓解,精神佳,睡眠时最低SaO2由治疗前的62．3± 6．7％升高至90．1±6．8％(P<0．01),减血氧饱和度由治疗前的31．5±4．2％降至6．0±4．1％(P<0．01);低通气次数由治疗前的 189．7±152．4降至6．4±5．1(P<0．01),阻塞性呼吸暂停次数由治疗前的212．5±134．5降至12．0±4．8(P<0．01);呼吸紊乱指数由治疗前的51．6±21．2降至5．0±3．1(P<0．01)。结论:CPAP的应用明显改善夜间气道阻塞,疗效果显著。应用CPAP时应指导患者正确使用呼吸方法,需在多导睡眠图的检测下确定最佳CPAP治疗压力才能完成。Objective.. To evaluate the effect of nCPAP on treting oOSAO. Methods： We 30 patients with OSAS were treated with OSAS between Febuary 2002 and August 2002, and noctul PSG monitor was used to evaluate the effect of CPAP ventilator on treating OSAS. Results： Work and study, work pressure of CPAP was 6-12 cmH20,average work pressure of CPAP was 10. 5 ± 3.4 cmH2O, CPAP can improve the symptom of OSAS. After treatment,the lowest SaO2 rose from 62.3 ±6.7% to 90. 1 ± 6. 8% obviously（P〈0. 01 ）, △Sa 02 decreased from 31.5 ±4, 2% to 6.0 ± 4. 1 % obviously（P〈0. 01 ）, the number of hypoventilation decreased from 189. 7 ±152. 4 to 6.4 ±5. 1 obviously （P〈0.01）, the number of obstructive apnea decreased from 212. 5 ± 134. 5 to 12.0 ± 4. 8 obviously （P〈0. 01 ）, RDI decreased from 51.6 ± 21.2 to 5.0 ± 3. 1（P〈0. 01）. Conclusion： CPAP can improve airway obstruct, treatment effect is good.

关 键 词：阻塞性睡眠呼吸暂停综合征 经鼻持续气道正压通气 多导睡眠图 

分 类 号：R56[医药卫生—呼吸系统]