小肠结肠炎耶氏菌实验性感染家兔微观病变观察  

On Microcosmic Pathogeny in Rabbits Experimentally Infected by Different Strains of Yersinia enterocolitica

作　　者：张爱联[1] 蔡仁平[1] 黄玉敏 

机构地区：[1]海南医学院附院检验科

出　　处：《海南大学学报（自然科学版）》1996年第2期177-181,共5页Natural Science Journal of Hainan University

摘　　要：应用透射电子显微镜观察致病性血清型带毒力质粒Ｙ．ｅ．Ｇ１５１及ＬＡＢ－Ｂ１８２菌株感染的家兔，其肠道及脾脏有微脓肿及菌落形成，在微脓肿形成的区域，组织细胞变性坏死严重．用ＬＡＢ—Ｂ１８２菌株感染的家兔，其肝脏可见局灶性凝固性坏死．在上述脏器无微脓肿及菌落形成的部位，肉眼观察正常，但在电子显微镜下．却呈现不同程度的组织细胞病变．细菌不在细胞内增殖．致病性血清型丢失毒力质粒的４３９—８０Ｖ－菌株感染的家兔，其肠道、肝脏及脾脏组织细胞无病理学改变．The rabbits inoculated with 6×108 Yersinia enterocolitica such as G151,LAB-B182and 439-80V-are observed through transmission electron microscope.The pathogenic serotypes and haboring virulence plasmids strains of Yersinia enterocolitica G 151 and LAB-B182 lead to micro-abscesses and colonies in those susceptible organs of the rabbits.There are a severe cells degeneration and necrosis in the tissues of forming micro-abscess and colonies,and there are also some pathologic changes in the tissues without micro-abscesses and colonies.However, the pathogenic serotypes and losting virulence plasmids strains of Yersinia enterocolitica-439-80V-have no pathogenic changes.The bacteria of Yersinia enterocolitica may possess invasiveness, but they don't multiply within the host cells.

关 键 词：小肠结肠炎 耶氏菌 电子显微镜 微观病变 感染 

分 类 号：R516.102[医药卫生—内科学]