旋光法测定盐酸左旋咪唑及其注射液含量  

Assay of levamisole hydrochloride and its injection by polarimetry

作　　者：张战伟 陈永华 宋传敏 

机构地区：[1]河南驻马店市天河动物药业有限公司,河南驻马店463000

出　　处：《中国兽药杂志》2006年第1期26-28,共3页Chinese Journal of Veterinary Drug

摘　　要：采用旋光法测定盐酸左旋咪唑及其注射液含量，结果表明，在4．000～6．500mg／mL浓度范围内，盐酸左旋咪唑的旋光度与浓度呈现良好的线性关系（r=0．9997，n=6）。与法定的非水滴定法相比较，旋光法具有简单、快速、易于操作等优点，且消除了非水滴定法中氯仿、高氯酸、冰乙酸等试剂对操作者及环境的危害。The method of determining levamisole hydrochloride and its injection by polarimetry was described. The results showed that the optical activity of levamisole hydrochloride was in good linear correlation with concentration （r =0. 9997, n = 6）. Comparing with the method of non-aqueous titration, it was sample, quickly and easy to operation.

关 键 词：盐酸左旋咪唑 注射液 旋光法 含量 

分 类 号：TQ460.72[医药卫生—药物分析学]