TMT(5-巯基-1,3,4-噻二唑-2-硫代乙酸)的合成  

Synthesis of TMT[5-Mercapto-1,3,4-Thiadiazol-2-ylsuIfanyl]-Acetic Acid

作　　者：于凯[1] 杨学富[1] 张大德[1] 姚祖光[1] 

机构地区：[1]华东理工大学,上海200237

出　　处：《影像技术》2005年第5期22-24,共3页Image Technology

摘　　要：TMT是一种重要的照相有机物中间体,可用于合成成色剂、防灰务剂、预灰化剂、稳定剂、增感剂、显影剂等方面,近年又广泛应用于医药、染料、农药等工业,本文介绍其合成方法。以二硫化碳、水合肼为原料,两步法合成5-巯基-1,3,4-噻二唑-2-硫代乙酸,该反应条件温和。操作简单。收率达到80％,适合工业化生产。并利用红外、质谱、液相色谱、元素分析对其进行了鉴定。TMT is an important intermediate for a series of photographic organic chemicals, e.g.color coupler,antifoggant,prefogging agent,stabilizer,sensitizer,developer etc,and recently,is widely used in pharmaceutical,dyestuff, pesticide industries etc,.this paper reports a method of its synthesis.Synthesis of TMT was successfully realized from carbon disulide and hydrazine hydrate through two steps under mild conditions,and the yield hits 80%.It was identified with IR,MS, HLCP and EA.

关 键 词：TMT DMTD 合成 

分 类 号：TQ572.4[化学工程—精细化工]