3×3设计中个体生物等效性评价的广义P-值法  

Assessment of Individual Bioequivalence in 3-sequence 3-period Crossover Designs Using Generalized P-value

作　　者：刘华[1] 

机构地区：[1]五邑大学数学物理系,广东江门529020

出　　处：《阜阳师范学院学报（自然科学版）》2005年第4期20-23,共4页Journal of Fuyang Normal University(Natural Science)

摘　　要：研究了个体生物等效性评价的统计方法,引入广义检验函数和广义P-值来评价个体生物等效性,并证明广 义P-值法在评价个体生物等效性的连续性．用广义P-值方法来评价个体生物等效性是一种有效的方法．In this article, the statistical methods of individual bioequivalence are studied,the generalized test function and the generalized p-value are introduced into the assessment of individual bioequivalence,and generalized p-value is proved to be continuous. The generalized p-value approach may be an effective method for assessing individual bioequivalence.

关 键 词：生物等效性 个体生物等效性 广义P-值 交叉设计 

分 类 号：O212[理学—概率论与数理统计]