128例宫颈支原体感染患者的药敏及治疗分析  

The drug sensitivity test and treatment study on 128 cases of endocervical mycoplasma infection

作　　者：梁影虹[1] 黄敏[1] 李倩[1] 

机构地区：[1]广东省佛山市南海区妇幼保健院妇产科,广东佛山528200

出　　处：《海南医学》2006年第2期50-52,共3页Hainan Medical Journal

摘　　要：目的了解宫颈支原体感染患者的药物敏感情况,探讨有效的临床治疗方法。方法(1)随机选择128例宫颈分泌物支原体培养阳性的患者,同时做药敏试验,找出敏感的抗菌素。(2)根据药敏结果分A组(交沙霉素联合强力霉素)、B组(交沙霉素)进行治疗,比较治愈率及不良反应。结果(1)强力霉素、美满霉素、交沙霉素、司帕沙星最为敏感的四种抗菌素,药敏率依次为96.1%、94.5%、93.0%、71.1%。(2)环丙沙星、罗红霉素、阿奇霉素、克拉霉素是耐药率最高的四种抗菌素,耐药率依次为39.8%、32.8%、32.8%、29.7%。(3)A组治疗一个疗程治愈率为83.1%,B组一个疗程治愈率53.3%,P<0.01为非常显著性差异,主要不良反应为胃肠道反应。结论(1)治疗本地区宫颈支原体感染患者时应选用强力霉素、美满霉素、交沙霉素、司帕沙星最为敏感的四种抗菌素。(2)强力霉素联合交沙霉素治疗宫颈支原体感染安全有效。Objective To study the drug sensitivity of mycoplasma and find out the effective treatment. Methods （1）Endocervical swabs were taken from 128 women with endocervical mycoplasma infection. The swabs were used for the drug sensitivity tests. （2） Josamyein and Doxycycline Hyclate were used in 60 cases as A group, Josamycin was used in other 60 cases as B group. The cure rate and side effects were compared between 2 groops. Results （1） Drag sensitivity rates to mycoplasma were Doxyeyclina Hyelate 96.1%, Minocycline Hydrochloride 94.5%, Josamycin 93.0%. Sparlloxacin 71.1%. （2） Drug resistance rates were Cipmfloxacin 39.8%, Roxithromycin 32.8%, Azithmmycin 32.8%, Clarithremycin29.7%. （3） The cure rote of A group was 83.1%, and 53.3% of B group. There had significant differences of the cure rates between 2 groups （P〈0.01）. Gastriontes tract reaction occurred in 2 groups, that was the major side-effect. Conclusions Doxycycline Hyclate, Minocycline Hydrochloride, josamycin, Spartloxacin were sensitive drug tested to mycoplasma. Josamycin and Doxycycline Hyclate can be used for treating the endecervical mycoplasma infection safely and effectively.

关 键 词：解脲脲原体感染 支原体感染 宫颈炎 抗菌素 交沙霉素 强力霉素 

分 类 号：R711.74[医药卫生—妇产科学]