新生儿机械通气时呼吸性碱中毒多因素分析  

Multifactor Analysis of Neonatal Respiratory Alkalosis During Mechanical Ventilation

作　　者：刘勇[1] 

机构地区：[1]湖北省妇幼保健院新生儿科,武汉430070

出　　处：《实用儿科临床杂志》2006年第2期93-94,共2页Journal of Applied Clinical Pediatrics

摘　　要：目的了解影响新生儿呼吸性碱中毒(呼碱)的发生因素并探讨解决方法。方法通过比较47例不同年份、孕周、体质量、肺部疾病、转归、上机时间新生儿呼碱发生率;呼碱和非呼碱时呼吸机参数,以发现影响呼碱发生因素。并对这些因素进行Logistic回归分析。结果不同孕周、原发病、通气方式之间,呼碱的发生率有显著性差异;呼碱组与非吸碱组呼气末正压(PEEP)、吸气时间(TI)有显著差异。经多因素回归分析显示,TI延长、PEEP提高和原发病是影响呼碱发生的重要因素。结论正确调节呼吸机参数并考虑不同疾病的性质,可减少呼碱发生。Objective To explore the factors which cause neonatal respiratory alkalosis and explore the solution to it. Methods Comparison of occurrence of respiratory alkalosis between different time, gestational weeks, body weight, lung illness, outcome, and mechanical ventilation parameters between respiratory alkslosis group and non - respiratory alkalosis group were performed to discover causes of respiratory alkalosis, then Logistic recession analysis for these causes were carried out. Results There were significant difference of occurrence of respiratory alkalosis between different gestational weeks,primary illness and ventilation mode;time of inspire positive end-expiratory pressure（PEEP） in respiratory alkalosis group was significantly higher than that in non - respiratory alkalosis group. Logistic recession analys was concealed that extended time of inspire, higher PEEP and different primary illness were risk factors which result in respiratory alkalosis. Conclusion The occurrence of respiratory alkalosis may be minimized by reasonable regulating and selecting of parameter of ventilation machine according to various diseases.

关 键 词：机械通气 碱中毒 呼吸性 婴儿 新生 

分 类 号：R722.1[医药卫生—儿科]