热致相分离技术制备组织工程支架  

Study on Preparation of Scaffold for Tissue Engineering by Thermally Induced Phase Separation Technique

作　　者：王克敏[1] 李世荣[2] 郭嘉[2] 

机构地区：[1]湖北省化学研究院,湖北武汉430074 [2]武汉化工学院湖北省新型反应器与绿色化学工艺重点实验室,湖北武汉430073

出　　处：《化学与生物工程》2006年第1期1-3,共3页Chemistry & Bioengineering

基　　金：国家自然科学基金资助项目(20376065)

摘　　要：用生物可降解材料制备细胞生长支架是组织工程的关键技术之一,而热致相分离技术是制备生物可降解三维多孔支架的重要方法。综述了凝胶浇铸、热致凝胶化、乳化/冷冻干燥、固液相分离和液液相分离等几种相分离技术的原理及应用,并预测了相分离技术的应用前景。Fabrication of scaffolds for cell growing from biodegradable materials is the key technique in tissue engineering. And thermally induced phase separation is one of important ways to prepare biodegradable three-dimensional porous scaffolds. In this paper, the principles of several phase separation techniques, such as gel casting, the combination of thermally induced gel, emulsion freezing-drying,solid-liquid phase separation and liquid-liquid phase separation, and their applications are reviewed,and the potential applications of phase separation are proposed as well.

关 键 词：热致相分离 三维支架 组织工程 

分 类 号：R318.08[医药卫生—生物医学工程]